VU 0255035
Cat. No.：YN322161
| 产品名称: | VU 0255035 |
| CAS No.: | 1135243-19-4 |
| Chemical Name: | N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide |
| Synonyms: | VU 255035 |
| 分子量: | 432.5 |
| 分子式: | C18H20N6O3S2 |
| SMILES: | O=C(CCNS(C1=CC=CC2=NSN=C21)(=O)=O)N(CC3)CCN3C4=CC=NC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VU 0255035 是一种高度选择性、竞争性、可透过血脑屏障的毒蕈碱 M1 受体拮抗剂，IC50为 130 nM。VU 0255035 可减少毛果芸香碱诱导的小鼠癫痫发作。VU 0255035 用于检测 M1 受体在不同情况下的作用。 |
| IC50和靶点: | |
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Harada, K., Matsuoka, H., Miyata, H., et al.Identification of muscarinic receptor subtypes involved in catecholamine secretion in adrenal medullary chromaffin cells by genetic deletionBr. J. Pharmacol.172(5),1348-1359(2015)
