TG6-129
Cat. No.：YN322169
| 产品名称: | TG6-129 |
| CAS No.: | 1164464-14-5 |
| Chemical Name: | (2E)-N-[[[4-[[(5-ethyl-1,3,4-thiadiazol-2-yl)amino]sulfonyl]phenyl]amino]thioxomethyl]-3-(4-fluorophenyl)-2-propenamide |
| Synonyms: | TG6-129; TG6 129; TG6129. |
| 分子量: | 491.6 |
| 分子式: | C20H18FN5O3S3 |
| SMILES: | FC1=CC=C(/C=C/C(NC(NC2=CC=C(S(NC3=NN=C(CC)S3)(=O)=O)C=C2)=S)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TG6-129 是一种选择性的EP2受体拮抗剂。TG6-129 可降低 butaprost 诱导的 P388D1 巨噬细胞中炎症因子的表达。 |
| IC50和靶点: | |
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Kawahara, K., Hohjoh, H., Inazumi, T., et al.Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptorsBiochim. Biophys. Acta1851(4),414-421(2015)
Ganesh, T., Jiang, J., Shashidharamurthy, R., et al.Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonistsACS Med. Chem. Lett.4(7),616-621(2013)
