ASP7657 free base
Cat. No.：YN322179
| 产品名称: | ASP7657 free base |
| CAS No.: | 1196045-28-9 |
| Chemical Name: | trans-4-[[[[1-(2-quinolinylmethyl)-5-(trifluoromethyl)-1H-indol-7-yl]carbonyl]amino]methyl]-cyclohexanecarboxylic acid |
| Synonyms: | ASP 7657;ASP-7657 |
| 分子量: | 509.5196696 |
| 分子式: | C28H26F3N3O3 |
| SMILES: | OC([C@H]1CC[C@H](CNC(C2=C(N(CC3=NC(C=CC=C4)=C4C=C3)C=C5)C5=CC(C(F)(F)F)=C2)=O)CC1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ASP7657 free base 是一种具有口服活性的EP4 受体拮抗剂，对人和大鼠 EP4 受体的Ki分别为 2.21 和 6.02 nM。 |
| IC50和靶点: | [{name:"hEP4:2.21 nM (IC50)"},{name: "rat EP4:6.02 nM (IC50)"}] |
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| Solvent & Solubility: |
Mizukami, K., Kamada, H., Yoshida, H., et al.Pharmacological properties of ASP7657, a novel, potent, and selective prostaglandin EP4 receptor antagonistNaunyn Schmiedebergs Arch. Pharmacol.391(12),1319-1326(2018)
