AC-265347
Cat. No.：YN322208
| 产品名称: | AC-265347 |
| CAS No.: | 1253901-26-6 |
| Chemical Name: | α-(2,4-dimethylphenyl)-α-methyl-2-benzothiazolemethanol |
| Synonyms: | AC265347 |
| 分子量: | 283.38902 |
| 分子式: | C17H17NOS |
| SMILES: | CC1=CC(C)=CC=C1C(C)(O)C2=NC3=CC=CC=C3S2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AC-265347 是一种钙敏感受体 (CaSR) 激动剂和正变构调节剂 (ago-PAM)，功能亲和力 (pKB) 为 5.1。AC-265347 可用于甲状旁腺功能亢进及相关疾病的研究。 |
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Ma, J.N., Owens, M., Gustafsson, M., et al.Characterization of highly efficacious allosteric agonists of the human calcium-sensing receptorJ. Pharmacol. Exp. Ther.337(1),275-284(2011)
Leach, K., Gregory, K.J., Kufareva, I., et al.Towards a structural understanding of allosteric drugs at the human calcium-sensing receptorCell Res.26(5),574-592(2016)
