MK-1903
Cat. No.:YN322216
CAS No. :1268882-43-4
产品名称: | MK-1903 |
CAS No.: | 1268882-43-4 |
Chemical Name: | 4,4aR,5,5aR-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid |
Synonyms: | |
分子量: | 164.1614 |
分子式: | C8H8N2O2 |
SMILES: | OC(C1=NNC2=C1C[C@@]3([H])[C@]2([H])C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MK-1903 是一种有效且选择性的羟基羧酸受体2 (HCA2, GPR109A) 的完全激动剂。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Boatman, P.D., Lauring, B., Schrader, T.O., et al.(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): A potent GPR109a agonist that lowers free fatty acids in humansJ. Med. Chem.55(8),3644-3666(2012)