VU 0360223
Cat. No.:YN322217
产品名称: | VU 0360223 |
CAS No.: | 1274859-33-4 |
Chemical Name: | 3-fluoro-5-(2-methyl-5-benzothiazolyl)-benzonitrile |
Synonyms: | |
分子量: | 268.3 |
分子式: | C15H9FN2S |
SMILES: | FC1=CC(C#N)=CC(C2=CC3=C(SC(C)=N3)C=C2)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | VU 0360223 是一种有效的代谢型谷氨酸受体 (mGluR)负变构调节剂,IC50为 61 nM。 |
IC50和靶点: | [{name:"mGluR:61 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Lindsley, C.W., Bates, B.S., Menon, U.N., et al.(3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: Discovery of a new tool compound with activity in the OSS mouse model of addictionACS Chem. Neurosci.2,471-482(2011)