AZ 12216052
Cat. No.：YN322220
| 产品名称: | AZ 12216052 |
| CAS No.: | 1290628-31-7 |
| Chemical Name: | 2-[[(4-bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]-acetamide |
| Synonyms: | AZ 12216052; AZ-12216052; AZ12216052 |
| 分子量: | 392.35412 |
| 分子式: | C19H22BrNOS |
| SMILES: | BrC1=CC=C(CSCC(NC2=CC=C(C(C)CC)C=C2)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZ 12216052 是一种mGluR8正变结构调节剂，帮助mGluR8调节视网膜神经节细胞的信号输入。AZ 12216052 具有抗焦虑作用。 |
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Duvoisin, R.M., Pfankuch, T., Wilson, J.M., et al.Acute pharmacological modulation of mGluR8 reduces measures of anxietyBehav. Brain Res.212(2),168-173(2010)
Jantas, D., Greda, A., Golda, S., et al.Neuroprotective effects of metabotropic glutamate receptor group II and III activators against MPP(+)-induced cell death in human neuroblastoma SH-SY5Y cells: The impact of cell differentiation stateNeuropharmacology83,36-53(2014)
