Pamoic acid
Cat. No.：YN322226
| 产品名称: | Pamoic acid |
| CAS No.: | 130-85-8 |
| Chemical Name: | 4,4'-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid] |
| Synonyms: | 帕莫酸 |
| 分子量: | 388.4 |
| 分子式: | C23H16O6 |
| SMILES: | OC(C1=CC(C=CC=C2)=C2C(CC3=C(C=CC=C4)C4=CC(C(O)=O)=C3O)=C1O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pamoic acid 是一种有效的GPR35激动剂，EC50为 79 nM。Pamoic acid 具有神经保护和抗炎特性。 |
| IC50和靶点: | |
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Zhao, P., Sharir, H., Kapur, A., et al.Targeting of the orphan receptor GPR35 by pamoic acid: A potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activityMol. Pharmacol.78(4),560-568(2010)
Neubig, R.R.Mind your salts: When the inactive constituent isn’tMol. Pharmacol.78(4),558-559(2010)
