PF9601N
Cat. No.：YN380334
CAS No. ：133845-63-3
| 产品名称: | PF9601N |
| CAS No.: | 133845-63-3 |
| Chemical Name: | 5-(phenylmethoxy)-N-2-propyn-1-yl-1H-indole-2-methanamine |
| Synonyms: | PF 9601N;5-(Phenylmethoxy)-N-2-propynyl- 1H-Indole-2-methanamine;FA-73;N-(2-Propynyl)-2-(5-benzyloxy-indolyl) methylamine;FA 73 |
| 分子量: | 290.3591 |
| 分子式: | C19H18N2O |
| SMILES: | C#CCNCC1=CC2=C(N1)C=CC(OCC3=CC=CC=C3)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF9601N 是一种单胺氧化酶 B (MAO-B) 抑制剂，在帕金森病 (PD) 的多种体内外模型中具有神经保护特性。PF9601N 可用于兴奋性毒性介导的神经退行性疾病的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Perez, V., and Unzeta, M.PF 9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine], a new MAO-B inhibitor, attenuates MPTP-induced depletion of striatal dopamine levels in C57/BL6 miceNeurochem. Int.42(3),221-229(2003)
Prat, G., Pérez, V., Rubi, A., et al.The novel type B MAO inhibitor PF9601N enhances the duration of L-DOPA-induced contralateral turning in 6-hydroxydopamine lesioned ratsJ. Neural Transm. (Vienna)107(4),409-417(2000)
