3,5-Bis(4-nitrophenoxy)benzoic acid
Cat. No.：YN380354
| 产品名称: | 3,5-Bis(4-nitrophenoxy)benzoic acid |
| CAS No.: | 173550-33-9 |
| Chemical Name: | |
| Synonyms: | 3,5-Bis(4-nitrophenoxy)benzoic acid |
| 分子量: | 396.30726 |
| 分子式: | C19H12N2O8 |
| SMILES: | O=C(C1=CC(OC2=CC=C([N+]([O-])=O)C=C2)=CC(OC3=CC=C([N+]([O-])=O)C=C3)=C1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3,5-Bis(4-nitrophenoxy)benzoic acid 是一种γ-secretase抑制剂。3,5-Bis(4-nitrophenoxy)benzoic acid 导致 Aβ42 和notch-1Aβ-like peptide 25 (Nβ25) 的释放水平降低。3,5-Bis(4-nitrophenoxy)benzoic acid 作为胎儿甲状腺功能减退的标志物，是母体血清中 3,3’-diiodothyronine sulfate (T2S) 的交叉反应物质。 |
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Okochi, M., Fukumori, A., Jiang, J., et al.Secretion of the Notch-1 Aβ-like peptide during Notch signalingJ. Biol. Chem.281(12),7890-7898(2006)
Sail, V., and Hadden, M.K.Identification of small molecule Hes1 modulators as potential anticancer chemotherapeuticsChem. Biol. Drug Des.81(3),334-342(2013)
