Divarasib
Cat. No.：YN322423
CAS No. ：2417987-45-0
规格
价格(RMB)
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| 产品名称: | Divarasib |
| CAS No.: | 2417987-45-0 |
| Chemical Name: | |
| Synonyms: | GDC-6036 |
| 分子量: | 622.06 |
| 分子式: | C29H32ClF4N7O2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Divarasib (GDC-6036) 是一种具有口服生物利用度，选择性的KRAS G12C抑制剂，IC50为 <0.01 μM。Divarasib 与 KRAS G12C 的开关 II (SW-II) 口袋共价结合，并将其不可逆地锁定在非活动的 GDP 结合状态。 |
| IC50和靶点: | [{name:"K-Ras(G12C):<0.01 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
