SF 11
Cat. No.：YN322515
CAS No. ：443292-81-7
规格
价格(RMB)
库存
| 产品名称: | SF 11 |
| CAS No.: | 443292-81-7 |
| Chemical Name: | N-(4-ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
| Synonyms: | |
| 分子量: | 446.60538 |
| 分子式: | C27H30N2O2S |
| SMILES: | S=C(N1CCC(C(C2=CC=CC=C2)(C3=CC=CC=C3)O)CC1)NC4=CC=C(C=C4)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SF 11是一种有效的脑渗透神经肽 YY2受体拮抗剂 (IC50=199 nM)。具有抗抑郁药样活性。 |
| IC50和靶点: | [{name:"NPY Y2 receptor:199 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Brothers, S.P., Saldanha, A., Spicer, T.P., et al.Selective and brain penetrant neuropeptide Y Y2 receptor antagonists discovered by whole-cell high-throughput screeningMol. Pharmacol.77(1),46-57(2010)
Domin, H., Piergies, N., Pięta, E., et al.Characterization of the brain penetrant neuropeptide Y Y2 receptor antagonist SF-11ACS Chem. Neurosci.10(8),3454-3463(2019)
