CAY10580
Cat. No.：YN322590
CAS No. ：64054-40-6
规格
价格(RMB)
库存
| 产品名称: | CAY10580 |
| CAS No.: | 64054-40-6 |
| Chemical Name: | 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid |
| Synonyms: | |
| 分子量: | 341.5 |
| 分子式: | C19H35NO4 |
| SMILES: | CCCCCC(O)CCC1CCC(=O)N1CCCCCCC(=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CAY10580是有效和选择性的前列腺素EP4受体 (EP4) 激动剂 (Ki=35 nM)。 |
| IC50和靶点: | [{name:"EP4:35 nM (Ki)"},{name: "EP2:3000 nM (Ki)"},{name: "EP3:2000 nM (Ki)"},{name: "EP1:>3000 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
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Babaev, V.R., Chew, J.D., Ding, L., et al.Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosisCell Metab.8(6),492-501(2008)
Billot, X., Chateauneuf, A., Chauret, N., et al.Discovery of a potent and selective agonist of the prostaglandin EP4 receptorBioorg. Med. Chem. Lett.13(6),1129-1132(2003)
Smith, R.L., Lee, T., Gould, N.P., et al.Prostaglandin isosteres. 1. (8-Aza-, 8,10-Diaza-, and 8-Aza-11-thia)-9-oxoprostanoic acids and their derivativesJ. Med. Chem.20(10),1292-1299(1977)
