Roxatidine
Cat. No.：YN322640
CAS No. ：78273-80-0
规格
价格(RMB)
库存
| 产品名称: | Roxatidine |
| CAS No.: | 78273-80-0 |
| Chemical Name: | 2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-acetamide |
| Synonyms: | |
| 分子量: | 306.40002 |
| 分子式: | C17H26N2O3 |
| SMILES: | O=C(CO)NCCCOC1=CC=CC(CN2CCCCC2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Roxatidine 是 Roxatidine acetate 的活性代谢产物，是组胺H2受体拮抗剂。Roxatidine 是抗溃疡药，抑制组胺释放（从而抑制质子分泌）并抑制炎症和血管生成的重要标志物 VEGF-1 的产生。具有抗过敏性炎症作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Sewing, K.-F., Beil, W., and Hannemann, H.Comparative pharmacology of histamine H2-receptor antagonistsDrugs35(Suppl. 3),25-29(1988)
Umegaki, E., Yoda, Y., Tokioka, S., et al.Protective effect of roxatidine against indomethacin induced small intestinal mucosal injury in ratsJ. Gastroenterol. Hepatol.25(Suppl. 1),S35-S40(2010)
