Desmethyl cariprazine
Cat. No.：YN322656
CAS No. ：839712-15-1
规格
价格(RMB)
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| 产品名称: | Desmethyl cariprazine |
| CAS No.: | 839712-15-1 |
| Chemical Name: | N-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N'-methyl Urea |
| Synonyms: | |
| 分子量: | 413.38 |
| 分子式: | C20H30Cl2N4O |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Desmethyl cariprazine 是 Cariprazine 的活性代谢产物。Cariprazine，是抗精神病有效剂候选活性分子，结合 D3, D2 和 5-HT1A 的 Ki为 0.085 nM，0.49 nM，2.6 nM。 |
| IC50和靶点: | [{name:"D3 Receptor:0.085 nM (Ki)"},{name: "D2 Receptor:0.49 nM (Ki)"},{name: "5-HT1A Receptor:2.6 nM (Ki)"}] |
| In Vitro: | |
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| Solvent & Solubility: |
Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010)
Seneca, N. et al.: Psychopharmacology, 218, 579 (2011)
Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)
