Benzoquinamide hydrochloride
Cat. No.：YN322846
| 产品名称: | Benzoquinamide hydrochloride |
| CAS No.: | 113-69-9 |
| Chemical Name: | 2-(Acetyloxy)-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizine-3-carboxamide Hydrochloride; Benzoquinamide Hydrochloride; |
| Synonyms: | P2647 hydrochloride; BZQ hydrochloride; Benzoquinamide hydrochloride |
| 分子量: | 440.96 |
| 分子式: | C22H33ClN2O5 |
| SMILES: | [H]Cl.CC(OC1C(C(N(CC)CC)=O)CN2CCC3=CC(OC)=C(OC)C=C3C2C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Benzquinamide (P2647) 是一种止吐剂, 并可以与α2A,α2B, 以及α2C肾上腺素能受体 (α2-AR) 结合，Ki值分别为 1,365, 691 和 545 nM。Benzquinamide 还抑制 P-糖蛋白介导的药物流出，并增强多药耐药细胞中抗癌药物的细胞毒性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Pinson, Koe., et al.: J. Med. Chem., 7, 635 (1964), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),
