A-582941 dihydrochloride
Cat. No.：YN322915
CAS No. ：848591-90-2
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| 产品名称: | A-582941 dihydrochloride |
| CAS No.: | 848591-90-2 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 280.375 |
| 分子式: | C17H20N4 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | A-582941 dihydrochloride 是一种有效的，选择性的和可透过血脑屏障的α7nAChR的部分激动剂，在大鼠脑膜和人额叶皮层的Ki值分别为 10.8 nM 和 16.7 nM。A-582941 dihydrochloride 以 150 nM 的Ki值与人5-HT3受体结合。A-582941 dihydrochloride 具有研究与各种神经退行性疾病和精神疾病相关的认知缺陷的潜力。 |
| IC50和靶点: | [{name:"α7 nAChR:10.8 nM (Ki, for rat α7 receptors)"},{name: "α7 nAChR:16.7 nM (Ki, for human α7 receptors)"},{name: "5-HT3 Receptor:150 nM (Ki)"}] |
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