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CL 316243

Cat. No.：138908-40-4

  • CAS No. ：138908-40-4

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    • 产品名称: CL 316243
      CAS No.: 138908-40-4
      Chemical Name:
      Synonyms:CL316243 disodium
      分子量:465.79
      分子式:C₂₀H₁₈ClNNa₂O₇
      SMILES:O=C(C1(C(O[Na])=O)OC2=CC=C(C[C@H](NC[C@@H](C3=CC=CC(Cl)=C3)O)C)C=C2O1)O[Na]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Bloom, J.D., Dutia, M.D., Johnson, B.D., et al.Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent β-adrenergic agonist virtually specific for β3 receptors. A promising antidiabetic and antiobesity agentJ. Med. Chem.35(16),3081-3084(1992)', 'Baker, J.G.The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptorsBr. J. Pharmacol.144(3),317-322(2005)', 'Guerra, C., Koza, R.A., Yamashita, H., et al.Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposityJ. Clin. Invest.102(2),412-420(1998)', 'MacPherson, R.E.K., Castellani, L., Bueadoin, M.S., et al.Evidence for fatty acids mediating CL 316,243-induced reductions in blood glucose in miceAm. J. Physiol. Endocrinol. Metab.307(7),E563-E570(2014)
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