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L755507

Cat. No.：159182-43-1

  • CAS No. ：159182-43-1

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    • 产品名称: L755507
      CAS No.: 159182-43-1
      Chemical Name:
      Synonyms:Benzenesulfonamide,4-[[(hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-;Benzenesulfonamide,4-[[(hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenox...;L755,507;L-755,507;L-755,507,4-[[
      分子量:584.73
      分子式:C₃₀H₄₀N₄O₆S
      SMILES:O=S(C1=CC=C(NC(NCCCCCC)=O)C=C1)(NC2=CC=C(CCNC[C@H](O)COC3=CC=C(O)C=C3)C=C2)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Parmee, E.R., Ok, H.O., Candelore, M.R., et al.Discovery of L-755,507: A subnanomolar humanβ3 adrenergic receptor agonistBioorg. Med. Chem. Lett.8(9),1107-1112(1998)', 'Yu, C., Liu, Y., Ma, T., et al.Small molecules enhance CRISPR genome editing in pluripotent stem cellsCell Stem Cell16(2),142-147(2015)', 'Sato, M., Hutchinson, D.S., Evans, B.A., et al.The β3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-ethyl]phenyl]benzenesulfonamide (L748337) activate different signaling pathways in Chinese hamster ovary-K1 cells stably expressing the human β3-adrenoceptorMol. Pharmacol.74(5),1417-1428(2008)
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