Bucindolol
Cat. No.：YN320250
CAS No. ：71119-11-4
| 产品名称: | Bucindolol |
| CAS No.: | 71119-11-4 |
| Chemical Name: | 2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]-benzonitrile |
| Synonyms: | |
| 分子量: | 363.45 |
| 分子式: | C₂₂H₂₅N₃O₂ |
| SMILES: | N#CC1=CC=CC=C1OCC(O)CNC(C)(C)CC2=CNC3=C2C=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bucindolol 是一种 β1 肾上腺素能受体 (β1-adrenergic receptor) 阻滞剂，具有内源性拟交感活性，用于心力衰竭疾病研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Bristow, M.R., Roden, R.I., Lowes, B.D., et al.The role of third-generation beta-blocking agents in chronic heart failureClin. Cardiol.21(12 Suppl 1),I3-I13(1998)
Maack, C., Cremers, B., Flesch, M., et al.Different intrinsic activities of bucindolol, carvedilol and metoprolol in human failing myocardiumBr. J. Pharmacol.130(5),1131-1139(2000)
Smart, N.A., Kwok, N., Holland, D.J., et al.Bucindolol: A pharmacogenomic perspective on its use in chronic heart failureClin. Med. Insights Cardiol.5,55-66(2011)
