Salmeterol-D3
Cat. No.：YN320744
| 产品名称: | Salmeterol-D3 |
| CAS No.: | 497063-94-2 |
| Chemical Name: | 6-hydroxy-α3-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethan-α1,α1,α3-d3-ol |
| Synonyms: | salmeterol-d3 (3-hydroxymethyl-d2, alpha-d1);SalMeterol-d3 |
| 分子量: | 418.58 |
| 分子式: | C₂₅H₃₄D₃NO₄ |
| SMILES: | OC([2H])([2H])C1=C(O)C=CC(C(CNCCCCCCOCCCCC2=CC=CC=C2)([2H])O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Salmeterol-D3 is the deuterium labeled Salmeterol (HY-14302). Salmeterol is a long-actingbeta2-adrenergic receptoragonist that is used for the study of asthma and chronic obstructive pulmonary disease (COPD). |
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Procopiou, P.A., Barrett, V.J., Ford, A.J., et al.The discovery of long-acting saligenin β2 adrenergic receptor agonists incorporating a urea groupBioorg. Med. Chem.19(20),6026-6032(2011)
Ball, D.I., Brittain, R.T., Coleman, R.A., et al.Salmeterol, a novel, long-acting β2-adrenoceptor agonist: Characterization of pharmacological activity in vitro and in vivoBr. J. Pharmacol.104(3),665-671(1991)
Isin, B., Estiu, G., Wiest, O., et al.Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probesPLoS One7(12),e50186(2012)
