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Camptothecin

Cat. No.：7689-03-4

  • CAS No. ：7689-03-4

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    • 产品名称: Camptothecin
      CAS No.: 7689-03-4
      Chemical Name:
      Synonyms:喜树碱; Campathecin; (S)-(+)
      分子量:348.35
      分子式:C₂₀H₁₆N₂O₄
      SMILES:O=C1C2=C([C@@](O)(CC)C(OC2)=O)C=C(N1C3)C(C3=C4)=NC5=C4C=CC=C5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 0.98
    • Drwal, M.N., Agama, K., Wakelin, L.P.G., et al.Exploring DNA topoisomerase I ligand space in search of novel anticancer agentsPLoS One6(9),1-12(2011)', 'Hsiang, Y.H., Hertzberg, R., Hecht, S., et al.Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase IJ. Biol. Chem.260(27),14873-14878(1985)', 'Marchand, C., Antony, S., Kohn, K.W., et al.A novel norindeniosoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complexMol. Cancer Ther.5(2),287-295(2006)', 'Dancey, J., and Eisenhauer, E.A.Current perspectives on camptothecins in cancer treatmentBr. J. Cancer74(3),327-338(1996)', 'Rothenberg, M.L.Topoisomerase I inhibitors: Review and updateAnn. Oncol.8(9),837-855(1997)
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