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Plicamycin

Cat. No.:18378-89-7

  • CAS No. :18378-89-7

    • 产品资料
    • 参考文献
    • 产品名称: Plicamycin
      CAS No.: 18378-89-7
      Chemical Name:
      Synonyms:Mithramycin A
      分子量:1085.15
      分子式:C₅₂H₇₆O₂₄
      SMILES:O=C([C@H]([C@@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])C1)O[C@@](O[C@H](C)[C@H]2O)([H])C[C@H]2O[C@@](O[C@H](C)[C@@H]3O)([H])C[C@H]3O[C@@](O[C@H](C)[C@H]4O)([H])C[C@@]4(O)C)C(C1=CC5=CC(O[C@H](O[C@H](C)[C@H]6O)C[C@H]6O[C@@](O[C@H](C)[C@H]7O)([H])C[C@H]7O)=C(
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • Sleiman, S.F., Berlin, J., Basso, M., et al.Histone deacetylase inhibitors and mithramycin A impact a similar neuroprotective pathway at a crossroad between cancer and neurodegenerationPharmaceuticals4,1183-1195(2011)', 'Sleiman, S.F., Langley, B.C., Basso, M., et al.Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegenerationJ. Neurosci.31(18),6858-6870(2011)', 'Lee, T.J., Jung, E.M., Lee, J.T., et al.Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sitesMol. Cancer Ther.5,2737-2746(2006)', 'Jia, Z., Gao, Y., Wang, L., et al.Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activityCancer Res.70,1111-1119(2010)', 'Duverger, V., Murphy, A.M., Sheehan, D., et al.The anticancer drug mithramycin A sensitises tumour cells to apoptosis induced by tumour necrosis factor (TNF)Br. J. Cancer90,2025-2031(2004)
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    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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