HIV-1 inhibitor-58
Cat. No.：YN251984
| 产品名称: | HIV-1 inhibitor-58 |
| CAS No.: | 1051418-95-1 |
| Chemical Name: | 11-cyclopropyl-2,2,3,3-d4-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one |
| Synonyms: | 奈韦拉平 d |
| 分子量: | 270.32226 |
| 分子式: | C15H10D4N4O |
| SMILES: | O=C1C2=C(N=CC=C2)N(C3C([2H])([2H])C3([2H])[2H])C4=C(C(C)=CC=N4)N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nevirapine-d4是 Nevirapine 的氘代物。Nevirapine (BI-RG 587) 是用于研究 HIV/AIDS 的HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM。 |
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Grobler, J.A., Dornadula, G., Rice, M.R., et al.HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitroJ. Biol. Chem.282(11),8005-8010(2007)
Grob, P.M., Cao, Y., Muchmore, E., et al.Prophylaxis against HIV-1 infection in chimpanzees by nevirapine, a nonnucleoside inhibitor of reverse transcriptaseNat. Med.3(6),665-670(1997)
