HIV-1 inhibitor-18
Cat. No.：YN252003
CAS No. ：1192224-24-0
规格
价格(RMB)
库存
| 产品名称: | HIV-1 inhibitor-18 |
| CAS No.: | 1192224-24-0 |
| Chemical Name: | (3S,8S,9S,12S)-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-2,5,6,10,13-pentaazatetradecanedioic acid 1,14-dimethyl ester |
| Synonyms: | FT-0665859 |
| 分子量: | 537.7 |
| 分子式: | C26H43N5O7 |
| SMILES: | O[C@@H](CNNC([C@@H](NC(OC)=O)C(C)(C)C)=O)[C@@H](NC([C@H](C(C)(C)C)NC(OC)=O)=O)CC1=CC=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Des(benzylpyridyl) Atazanavir (compound M1) 是一种 N-脱烷基Atazanavir(HY-17367) 代谢物。Atazanavir 是一种高选择性HIV-1蛋白酶抑制剂。Des(benzylpyridyl) Atazanavir 可能有助于 Atazanavir 的有效性，但也可能有助于其毒性和相互作用。Des(benzylpyridyl) Atazanavir 可用于进一步研究 Atazanavir 的作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
ter Heine, R., Hillebrand, M.J.X., Rosing, H., et al.Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitorDrug Metab. Dispos.37(9),1826-1840(2009)
Li, F., Lu, J., Wang, L., et al.CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolismDrug Metab. Dispos.39(3),394-401(2011)
