Isavuconazole-d
Cat. No.：YN252035
| 产品名称: | Isavuconazole-d |
| CAS No.: | 1346598-58-0 |
| Chemical Name: | 4-(2-((2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)thiazol-4-yl)benzonitrile-2,3,5,6-d4 |
| Synonyms: | BAL-4815-d; RO-0094815-d |
| 分子量: | 441.4905264 |
| 分子式: | C22H13D4F2N5OS |
| SMILES: | FC(C=CC(F)=C1)=C1[C@](CN2N=CN=C2)(O)[C@@H](C)C3=NC(C4=C([2H])C([2H])=C(C#N)C([2H])=C4[2H])=CS3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isavuconazole-d4是 Isavuconazole (BAL-4815) 的氘代物。Isavuconazole 是一种三唑类前体，对酵母、霉菌和二型真菌具有抗真菌活性。 |
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Yamazaki, T., Inagaki, Y., Fujii, T., et al.In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from JapanInt. J. Antimicrob. Agents36(4),324-331(2010)
Rudramurthy, S.M., Chakrabarti, A., Geertsen, E., et al.In vitro activity of isavuconazole against 208 Aspergillus flavus isolates in comparison with 7 other antifungal agents: Assessment according to the methodology of the European Committee on Antimicrobial Susceptibility TestingDiagn. Microbiol. Infect. Dis.71(4),370-377(2011)
Datta, K., Rhee, P., Byrnes, E., III, et al.Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibilityJ. Clin. Microbiol.51(9),3090-3093(2013)
Astvad, K.M.T., Hare, R.K., and Arendrup, M.C.Evaluation of the in vitro activity of isavuconazole and comparator voriconazole against 2635 contemporary clinical Candida and Aspergillus isolatesClin. Microbiol. Infect.23(11),882-887(2017)
