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Neamine tetrahydrochloride

Cat. No.:YN252069

  • CAS No. :15446-43-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Neamine tetrahydrochloride
      CAS No.: 15446-43-2
      Chemical Name: 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine, tetrahydrochloride
      Synonyms:新霉胺四盐酸盐
      分子量:468.2
      分子式:C12H26N4O6 • 4HCl
      SMILES:O[C@H]1[C@H](O[C@@]2([H])O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2N)[C@@H](N)C[C@@H](N)[C@@H]1O.Cl.Cl.Cl.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Neamine tetrahydrochloride ,一种新霉素的降解产物,是一种广谱氨基糖苷类抗生素。Neamine tetrahydrochloride 是靶向血管生成素 (angiogenin) 的抗血管生成剂。Neamine tetrahydrochloride 具有有效的抗菌,抗肿瘤和神经保护活性。
      IC50和靶点:
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    • Greenberg, W.A., Priestley, E.S., Sears, P.S., et al.Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translationJ. Am. Chem. Soc.121(28),6527-6541(1999)

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