ISRIB (trans-isomer)
Cat. No.：YN270178
CAS No. ：1597403-47-8
| 产品名称: | ISRIB (trans-isomer) |
| CAS No.: | 1597403-47-8 |
| Chemical Name: | N,N′-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide |
| Synonyms: | trans-isomer,ISRIB,ISRIB trans-isomer,trans-ISRIB |
| 分子量: | 451.34 |
| 分子式: | C₂₂H₂₄Cl₂N₂O₄ |
| SMILES: | O=C(N[C@@H]1CC[C@@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ISRIB (trans-isomer)是高效的PERK抑制剂，IC50值为5 nM。 |
| IC50和靶点: | [{name:"PERK:5 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sidrauski, C., Acosta-Alvear, D., Khoutorsky, A., et al.Pharmacological brake-release of mRNA translation enhances cognitive memoryElife2,1-22(2013)
