MI-3
Cat. No.：YN270300
CAS No. ：1271738-59-0
规格
价格(RMB)
库存
| 产品名称: | MI-3 |
| CAS No.: | 1271738-59-0 |
| Chemical Name: | 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-(1-methylethyl)-thieno[2,3-d]pyrimidine |
| Synonyms: | Menin-MLL inhibitor 3 |
| 分子量: | 375.55 |
| 分子式: | C₁₈H₂₅N₅S₂ |
| SMILES: | CC(C)C1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MI-3 (Menin-MLL inhibitor 3) 是一种有效且高亲和力的menin-MLL抑制剂，IC50值为 648 nM，Kd值为 201 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Grembecka, J., He, S., Shi, A., et al.Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemiaNat. Chem. Biol.8(3),277-284(2012)
