PHA-680632
Cat. No.：YN290040
CAS No. ：398493-79-3
| 产品名称: | PHA-680632 |
| CAS No.: | 398493-79-3 |
| Chemical Name: | N-(2,6-diethylphenyl)-4,6-dihydro-3-[[4-(4-methyl-1-piperazinyl)benzoyl]amino]-pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide |
| Synonyms: | PHA 680632,PHA680632 |
| 分子量: | 501.62 |
| 分子式: | C₂₈H₃₅N₇O₂ |
| SMILES: | O=C(N1CC2=C(NN=C2NC(C3=CC=C(N4CCN(C)CC4)C=C3)=O)C1)NC5=C(C=CC=C5CC)CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PHA-680632是极光激酶抑制剂 (aurora)，对aurora A，B和C的IC50值分别为27，135和120 nM。 |
| IC50和靶点: | [{name:"Aurora A:27 nM (IC50)"},{name: "Aurora B:135 nM (IC50)"},{name: "Aurora C:120 nM (IC50)"}] |
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| Solvent & Solubility: |
Soncini, C., Carpinelli, P., Gianellini, L., et al.PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activityClin. Cancer Res.12(13),4080-4089(2006)
