HALOFUGINONE LACTATE
Cat. No.：YN291020
| 产品名称: | HALOFUGINONE LACTATE |
| CAS No.: | 82186-71-8 |
| Chemical Name: | Propanoic acid, 2-hydroxy-, compd. with rel-7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone; 2-Hydroxy-propanoic acid compd. with trans-(±)-7-bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-ox |
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| 分子量: | 504.76 |
| 分子式: | C19H23BrClN3O6 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | HALOFUGINONE LACTATE 是 febrifugine 的卤化衍生物，它是一种天然的含有喹唑啉酮的化合物，存在于中草药 D. febrifuga 中。Halofuginone 以 ATP 依赖性方式抑制脯氨酰-tRNA 合成酶，Ki 为 18.3 nM。 Halofuginone 是 I 型胶原合成的特异性抑制剂，通过抑制 TGF-β 活性来减轻骨关节炎 (OA) |
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| Solvent & Solubility: |
Ryley, J.G., et al.: Parasitology, 70, 203 (1975)
