Terazosin hydrochloride
Cat. No.:YN321468
| 产品名称: | Terazosin hydrochloride |
| CAS No.: | 63074-08-8 |
| Chemical Name: | [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone, monohydrochloride |
| Synonyms: | 盐酸特拉唑嗪 |
| 分子量: | 423.89 |
| 分子式: | C₁₉H₂₆ClN₅O₄ |
| SMILES: | O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OCCC4.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Terazosin hydrochloride 是一种喹唑啉衍生物,也是一种竞争性和口服活性的 α1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂。Terazosin hydrochloride 通过舒张血管和打开膀胱来起作用。Terazosin hydrochloride 可用于良性前列腺增生 (BPH) 和高血压的研究。 |
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Hancock, A.A., Buckner, S.A., Ireland, L.M., et al.Actions of terazosin and its enantiomers at subtypes of α- and α2-adrenoceptors in vitroJ. Recept. Signal Transduct. Res.15(7-8),863-885(1995)
Kyncl, J.J.Pharmacology of terazosinAm. J. Med.80(5B),12-19(1986)
Cohen, J.D.Long-term efficacy and safety of terazosin alone and in combination with other antihypertensive agentsAm. Heart J.122(3 Pt 2),919-925(1991)
Lepor, H., Williford, W.O., Barry, M.J., et al.The efficacy of terazosin, finasteride, or both in benign prostatic hyperplasiaN. Engl. J. Med.335(8),533-539(1996)