2′,3′,5′-Triacetyl-5-azacytidine
Cat. No.：YN310387
| 产品名称: | 2′,3′,5′-Triacetyl-5-azacytidine |
| CAS No.: | 10302-78-0 |
| Chemical Name: | 4-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one |
| Synonyms: | |
| 分子量: | 370.3 |
| 分子式: | C14H18N4O8 |
| SMILES: | O=C1N([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)C=NC(N)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2',3',5'-Triacetyl-5-azacytidine 是一种具有口服活性的 5-Azacytidine 前体。 5-Azacytidine 是 DNA 甲基转移酶的抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ziemba, A., Hayes, E., Freeman, B.B., III, et al.Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidineChemother. Res. Pract.2011(1),965826(2011)
Lucera, M.B., Fleissner, Z., Tabler, C.O., et al.HIV signaling through CD4 and CCR5 activates Rho family GTPases that are required for optimal infection of primary CD4+ T cellsRetrovirology14(1),4(2017)
