ARQ 621
Cat. No.：YN290571
| 产品名称: | ARQ 621 |
| CAS No.: | 1095253-39-6 |
| Chemical Name: | N-(3-aminopropyl)-3-chloro-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylamino)-2-quinazolinyl]-3-butyn-1-yl]-2-fluoro-benzamide |
| Synonyms: | ARQ-621,ARQ621 |
| 分子量: | 552.4264632 |
| 分子式: | C28H24Cl2FN5O2 |
| SMILES: | O=C(C1=C(C(Cl)=CC=C1)F)N(CCCN)[C@@H](C(N2NC3=CC=CC=C3)=NC4=CC(Cl)=CC=C4C2=O)CC#C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ARQ 621 是一种变构的有效的选择性Eg5抑制剂，Eg5 是一种参与细胞分裂的基于微管的 ATPase 运动蛋白。ARQ 621 具有抗肿瘤活性。ARQ 621 是一种驱动蛋白 (kinesin) 抑制剂。 |
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Jeay, S., Ali, S., Chen, C.-R., et al.Discovery of a novel Eg5 kinesin inhibitor, ARQ 621, with potent antitumor activity while sparing bone marrow-derived cellsCancer Res.68(9 Suppl.),656(2008)
