PKC-theta inhibitor 1
Cat. No.:YN310395
产品名称: | PKC-theta inhibitor 1 |
CAS No.: | 1160501-81-4 |
Chemical Name: | |
Synonyms: | PKCθ-IN-22 |
分子量: | 348.32 |
分子式: | C17H15F3N4O |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PKC-theta inhibitor 1 是PKCθ抑制剂,Ki值为 6 nM,在体内抑制IL-2产生,IC50为 0.19 μM。PKC-theta inhibitor 1 减轻了多发性硬化小鼠模型中疾病症状。 |
IC50和靶点: | [{name:"PKCθ:6 nM (Ki)"},{name: "PKCδ:392 μM (Ki)"},{name: "PKCα:1020 μM (Ki)"},{name: "IL-2 production:0.19 μM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |