ON1231320
Cat. No.：YN290603
CAS No. ：1312471-39-8
| 产品名称: | ON1231320 |
| CAS No.: | 1312471-39-8 |
| Chemical Name: | |
| Synonyms: | 7ao |
| 分子量: | 467.45 |
| 分子式: | C₂₂H₁₅F₂N₅O₃S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ON1231320 是一种高度特异性的 polo 样激酶 2 (PLK2) 抑制剂，IC50为 0.31 µM。ON1231320 在有丝分裂 G2/M 期阻断肿瘤细胞周期进程，导致细胞凋亡。ON1231320 是一种芳基磺酰基吡啶并嘧啶酮，具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"PLK2:0.31 μM (IC50)"},{name: "PLK1:>10 μM (IC50)"},{name: "PLK3:>10 μM (IC50)"},{name: "PLK4:>10 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
