PARP1-IN-11
Cat. No.:YN290643
CAS No. :1563007-08-8
产品名称: | PARP1-IN-11 |
CAS No.: | 1563007-08-8 |
Chemical Name: | 3,5,7,8-tetrahydro-2-[4-[2-(methylsulfonyl)phenyl]-1-piperazinyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
Synonyms: | |
分子量: | 406.5 |
分子式: | C18H22N4O3S2 |
SMILES: | O=C(N=C(N1CCN(C2=C(S(C)(=O)=O)C=CC=C2)CC1)N3)C4=C3CCSC4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | G244-LM 是一种有效且特异的tankyrase 1/2抑制剂,可抑制Wnt信号传导。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |
Lau, T., Chan, E., Callow, M., et al.A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growthCancer Res.73(10),3132-3144(2013)