Methylene blue hydrate
Cat. No.：YN290795
| 产品名称: | Methylene blue hydrate |
| CAS No.: | 65664-81-5 |
| Chemical Name: | 4,4'-bis(phenylamino)-[1,1'-binaphthalene]-5,5'-disulfonic acid, dipotassium salt |
| Synonyms: | Bis-ANS dipotassium |
| 分子量: | 672.85556 |
| 分子式: | C32H22N2O6S2 • 2K |
| SMILES: | [O-]S(C1=CC=CC2=C1C(NC3=CC=CC=C3)=CC=C2C4=C(C=CC=C5S([O-])(=O)=O)C5=C(NC6=CC=CC=C6)C=C4)(=O)=O.[K+].[K+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bis-ANS dipotassium 是一种蛋白质荧光探针，Bis-ANS 结合到tubulin，Kd为 2 μM。Bis-ANS dipotassium 是一种有效的蛋白质液-液相分离 (LLPS) 的双相调节剂。Bis-ANS dipotassium 低浓度促进 LLPS，高浓度抑制 LLPS。 |
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Hawe, A., Sutter, M., and Jiskoot, W.Extrinsic fluorescent dyes as tools for protein characterizationPharm. Res.25(7),1487-1499(2008)
Bothra, A., Bhattacharyya, A., Mukhopadhyay, C., et al.A fluorescence spectroscopic and molecular dynamics study of bis-ANS/protein interactionJ. Biomol. Struct. Dyn.15(5),959-966(1998)
Pastukhov, A.V., and Ropson, I.J.Fluorescent dyes as probes to study lipid-binding proteinsProteins53(3),607-615(2003)
Mozes, E., Hunya, A., Toth, A., et al.A novel application of the fluorescent dye bis-ANS for labeling neurons in acute brain slicesBrain Res. Bull.86(3-4),217-221(2011)
Horowitz, P., Prasad, V., and Luduena, R.F.Bis(1,8-anilinonaphthalenesulfonate). A novel and potent inhibitor of microtubule assemblyJ. Biol. Chem.259(23),14647-14650(1984)
Mazumdar, M., Parrack, P.K., Mukhupadbhyay, K., et al.Bis-ANS as a specific inhibitor for microtubule-associated protein induced assembly of tubulinBiochemistry31(28),6470-6474(1992)
