5'-O-DMT-N2-ibu-dG
Cat. No.：YN290800
| 产品名称: | 5'-O-DMT-N2-ibu-dG |
| CAS No.: | 68892-41-1 |
| Chemical Name: | 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)-guanosine |
| Synonyms: | N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl |
| 分子量: | 639.69778 |
| 分子式: | C35H37N5O7 |
| SMILES: | O=C1N=C(NC(C(C)C)=O)NC2=C1N=CN2[C@@]3([H])C[C@H](O)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=CC=C5)C6=CC=C(OC)C=C6)O3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 5'-O-DMT-N2-ibu-dG (N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine) 是一种脱氧核苷，可用于寡核苷酸的制备。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Wilk, A., Grajkowski, A., Phillips, L.R., et al.The 4-[N-Methyl-N-(2,2,2-trifluoroacetyl)amino]butyl group as an alternative to the 2-cyanoethyl group for phosphate protection in the synthesis of oligodeoxyribonucleotidesJ. Org. Chem.64(20),7515-7522(1999)
Grajkowski, A., Pedras-Vasconcelos, J., Wang, V., et al.Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic prodrugsNucleic Acids Res.33(11),3550-3560(2005)
Cieślak, J., and Beaucage, S.L.Thermolytic properties of 3-(2-pyridyl)-1-propyl and 2-[N-methyl-N-(2-pyridyl)]aminoethyl phosphate/thiophosphate protecting groups in solid-phase synthesis of oligodeoxyribonucleotidesJ. Org. Chem.68(26),10123-10129(2003)
