(E/Z)-GO289
Cat. No.:YN290802
CAS No. :694522-87-7
产品名称: | (E/Z)-GO289 |
CAS No.: | 694522-87-7 |
Chemical Name: | (E)-5-Bromo-2-methoxy-4-(((3-(methylthio)-5-phenyl-4H-1,2,4-triazol-4-yl)imino)methyl)phenol |
Synonyms: | GO289|GO-289;GO 289 |
分子量: | 419.297 |
分子式: | C17H15BrN4O2S |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (E/Z)-GO289 是一种有效且选择性的酪蛋白激酶 2(CK2)抑制剂 (IC50=7 nM)。(E/Z)-GO289 强烈延长昼夜节律周期。(E/Z)-GO289 表现出与细胞时钟功能相关的对癌细胞生长的细胞类型依赖性抑制。 |
IC50和靶点: | |
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Oshima, T., et al.: Sci. Adv., 5, eaau9060 (2019)