Troglitazone-d
Cat. No.:YN290804
产品名称: | Troglitazone-d |
CAS No.: | 702680-17-9 |
Chemical Name: | 2-methyl-2-[3-[(3S)-1-[2-[4-(1-methylethyl)phenyl]acetyl]-3-piperidinyl]phenoxy]-propanoic acid |
Synonyms: | CP-775146; CP 775146; CP775146. |
分子量: | 423.54456 |
分子式: | C26H33NO4 |
SMILES: | O=C(CC1=CC=C(C(C)C)C=C1)N2CCC[C@@H](C3=CC=CC(OC(C)(C)C(O)=O)=C3)C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CP-775146 是一种新的选择性PPARα激动剂,与PPARα配体强烈结合。CP-775146 有效缓解肥胖引起的肝损伤,通过激活肝脏脂肪酸 β-氧化途径防止脂质积累。 |
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Kane, C.D., Stevens, K.A., Fischer, J.E., et al.Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivoMol. Pharmacol.75(2),296-306(2009)