ZLN024
Cat. No.：YN310522
| 产品名称: | ZLN024 |
| CAS No.: | 723249-01-2 |
| Chemical Name: | 2-[[2-(2-bromo-4-methylphenoxy)ethyl]thio]-pyrimidine |
| Synonyms: | ZLN-024 hydrochloride |
| 分子量: | 325.2 |
| 分子式: | C13H13BrN2OS |
| SMILES: | CC1=CC(Br)=C(OCCSC2=NC=CC=N2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ZLN024 是一种AMPK变构激活剂。ZLN024 直接激活重组AMPK α1β1γ1，AMPK α2β1γ1，AMPK α1β2γ1和AMPK α2β2γ1异源三聚体，EC50分别为 0.42 μM，0.95 μM，1.1 μM 和 0.13 μM。 |
| IC50和靶点: | [{name:"AMPK α1β1γ1:0.42 μM (EC50)"},{name: "AMPK α2β1γ1:0.95 μM (EC50)"},{name: "AMPK α2β2γ1:0.13 μM (EC50)"}] |
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| Solvent & Solubility: |
Zhang, L.-N., Xu, L., Zhou, H.-Y., et al.Novel small-molecule AMP-activated protein kinase allosteric activator with beneficial effects in db/db mice.PLoS One8(8),e72092(2013)
