HS-243
Cat. No.：YN290816
CAS No. ：848249-10-5
| 产品名称: | HS-243 |
| CAS No.: | 848249-10-5 |
| Chemical Name: | |
| Synonyms: | HS243 |
| 分子量: | 324.33 |
| 分子式: | C17H16N4O3 |
| SMILES: | CCCN1C(NC2=CC=CC=C12)=NC(=O)C3=CC(=CC=C3)[N+]([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | HS-243 是一种有效且选择性的IRAK-4和IRAK-1抑制剂，IC50为 20 和 24 nM。HS-243 对TAK1(转化生长因子 β 活化激酶 1) 有微弱的抑制活性，IC50为 0.5 μM。HS-243 具有抗炎和抗癌活性。 |
| IC50和靶点: | [{name:"IRAK4:20 nM (IC50)"},{name: "IRAK-1:24 nM (IC50)"},{name: "CLK4:662 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
