Ruboxistaurin
Cat. No.：YN310538
CAS No. ：169939-94-0
规格
价格(RMB)
库存
| 产品名称: | Ruboxistaurin |
| CAS No.: | 169939-94-0 |
| Chemical Name: | |
| Synonyms: | LY333531 |
| 分子量: | 468.55 |
| 分子式: | C28H28N4O3 |
| SMILES: | O=C1NC(C(C2=CN(C3=CC=CC=C32)CCO[C@H](CN(C)C)CC4)=C1C5=CN4C6=CC=CC=C56)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ruboxistaurin (LY333531) 是一种具有口服活性，选择性PKCbeta抑制剂(Ki=2 nM)，Ruboxistaurin 表现出 ATP 依赖的竞争性抑制PKCbeta I，其IC50为4.7 nM。Ruboxistaurin 对PKCbeta II 的IC50为 5.9 nM。 |
| IC50和靶点: | [{name:"PKC-βI:4.7 nM (IC50)"},{name: "PKC-βII:5.9 nM (IC50)"},{name: "PKCη:52 nM (IC50)"},{name: "PKCδ:250 nM (IC50)"},{name: "PKCγ:300 nM (IC50)"},{name: "PKCα:360 nM (IC50)"},{name: "PKCε:600 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
