Tyk2-IN-7
Cat. No.：YN310562
CAS No. ：1609391-90-3
规格
价格(RMB)
库存
| 产品名称: | Tyk2-IN-7 |
| CAS No.: | 1609391-90-3 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 401.46 |
| 分子式: | C18H18N6O3S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tyk2-IN-7 是TYK2JH2抑制剂，与TYK2JH2 结构域结合，IC50和Ki.app分别为 0.00053 μM 和 0.00007 μM。Tyk2-IN-7 是常规TYK2正构抑制剂的高选择性替代，抑制 TYK2/JAK1/JAK2 激酶结构域。Tyk2-IN-7 抑制小鼠IL-12诱导的 IFNγ 药效学模型中以及抑制在IL-23和IL-12依赖性小鼠结肠炎模型中的功效。 |
| IC50和靶点: | [{name:"Tyk2 JH2:0.00053 μM (IC50)"},{name: "Tyk2 JH2:0.00007 μM (Ki app)"}] |
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