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AFN-1252

Cat. No.：620175-39-5

  • CAS No. ：620175-39-5

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    • 产品名称: AFN-1252
      CAS No.: 620175-39-5
      Chemical Name:
      Synonyms:API-1252; Debio 1452
      分子量:375.42
      分子式:C₂₂H₂₁N₃O₃
      SMILES:O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C(C=C3CC4)=CNC3=NC4=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 0.98
    • Kaplan, N.O., Albert, M., Awrey, D.E., et al.Mode of action, in vitro activity, and in vivo efficacy of AFN-1252, a selective antistaphylococcal FabI inhibitorAntimicrob. Agents Chemother.56(11),5865-5874(2012)', 'Parsons, J.B., Frank, M.W., Subramanian, S., et al.Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitorsProc. Natl. Acad. Sci. USA108(37),15378-15383(2011)', 'Karlowsky, J.A., Kaplan, N.O., Hafkin, B., et al.AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activityAntimicrob. Agents Chemother.53(8),3544-3548(2009)
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