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Brivudine

Cat. No.:YN250496

  • CAS No. :69304-47-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Brivudine
      CAS No.: 69304-47-8
      Chemical Name: 5-[(1E)-2-bromoethenyl]-2′-deoxy-uridine
      Synonyms:溴夫定; Bromovinyldeoxyuridine; BVDU
      分子量:333.14
      分子式:C₁₁H₁₃BrN₂O₅
      SMILES:OC[C@@H]1[C@H](C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Brivudine是具有抗病毒活性的胸苷类似物,用于早期急性带状疱疹的研究。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • De Clercq, E., Desgranges, C., Herdewijn, P., et al.Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridineJ. Med. Chem.29(2),213-217(1986)

      Kulikowski, T.Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A reviewPharm. World Sci.16(2),127-138(1994)

      De Clercq, E., Descamps, J., Verhelst, G., et al.Antiviral activity of 5-(2-halogenovinyl)-2'-deoxyuridinesCurr. Chemother. Infect. Dis.2,1372-1374(1980)

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