RS-1
Cat. No.：YN290466
CAS No. ：312756-74-4
| 产品名称: | RS-1 |
| CAS No.: | 312756-74-4 |
| Chemical Name: | 4-bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]-benzamide |
| Synonyms: | RS1,RS 1 |
| 分子量: | 524.23 |
| 分子式: | C₂₀H₁₆Br₂N₂O₃S |
| SMILES: | O=C(NC1=CC=C(Br)C=C1)C2=CC=C(Br)C(S(=O)(NCC3=CC=CC=C3)=O)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RS-1 是一种RAD51的激活剂，同时可增强CRISPR/Cas9的活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Jayathilaka, K., Sheridan, S.D., Bold, T.D., et al.A chemical compound that stimulates the human homologous recombination protein RAD51Proc. Natl. Acad. Sci. USA105(41),15848-15853(2008)
Pinder, J., Salsman, J., and Dellaire, G.Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editingNucleic Acids Res.43(19),9379-9392(2015)
Pan, Y., SHen, N., Jung-Klawitter, S., et al.CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria modelSci. Rep.6,65794(2016)
Song, J., Yang, D., Xu, J., et al.RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiencyNat. Commun.7,10548(2016)
