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Fluphenazine dihydrochloride

Cat. No.:YN1441175

  • CAS No. :146-56-5

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    • 产品名称: Fluphenazine dihydrochloride
      CAS No.: 146-56-5
      Chemical Name: 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol, dihydrochloride
      Synonyms:盐酸氟奋乃静
      分子量:510.44
      分子式:C₂₂H₂₈Cl₂F₃N₃OS
      SMILES:OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(C(F)(F)F)C=C24)CC1.[H]Cl.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Fluphenazine二盐酸盐是多巴胺受体D1/D2抑制剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Meltzer, H.Y., Matsubara, S., and Lee, J.-C.Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi valuesJ. Pharmacol. Exp. Ther.251(1),238-246(1989)

      Weiner, D.M., Burstein, E.S., Nash, N.R., et al.5-hydroxytryptamine2A receptor inverse agonists as antipsychoticsJ. Pharmacol. Exp. Ther.299(1),268-276(2001)

      Appl, H., Holzammer, T., Dove, S., et al.Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychoticsNaunyn-Schmiedebergs Arch. Pharmacol.385(2),145-170(2012)

      Kovacic, B., and Domino, E.F.Fluphenazine-induced acute and tardive dyskinesias in monkeysPsychopharmacology (Berl.)84(3),310-314(1984)

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