Molindone hydrochloride
Cat. No.：YN1730099
CAS No. ：15622-65-8
规格
价格(RMB)
库存
| 产品名称: | Molindone hydrochloride |
| CAS No.: | 15622-65-8 |
| Chemical Name: | 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one, monohydrochloride |
| Synonyms: | EN-1733A |
| 分子量: | 312.83 |
| 分子式: | C₁₆H₂₅ClN₂O₂ |
| SMILES: | O=C1C2=C(NC(C)=C2CC)CCC1CN3CCOCC3.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Molindone hydrochloride (EN-1733A) 是一种抗精神病药，有潜力用于精神分裂症的研究，可以通过阻断大脑中多巴胺的作用，从而降低精神病。 |
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Andersen, P.H.Comparison of the pharmacological characteristics of [3H]raclopride and [3H]SCH 23390 binding to dopamine receptors in vivo in mouse brainEur. J. Pharmacol.146(1),113-120(1988)
Bunney, B.S., Roth, R.H., and Aghajanian, G.K.Effects of molindone on central dopaminergic neuronal activity and metabolism: Similarity to other neurolepticsPsychopharmacol. Commun.1(4),349-358(1975)
Rubin, A.A., Yen, H.C., and Pfeffer, M.Psychopharmacological profile of molindoneNature216(5115),578-579(1967)
Balsara, J.J., Nandal, N.V., Gada, V.P., et al.Antagonism of bromocriptine-induced cage climbing behaviour in mice by the selective D-2 dopamine receptor antagonists, metoclopramide and molindoneIndian J. Physiol. Pharmacol.30(1),85-90(1986)
Poling, A., Cleary, J., Berens, K., et al.Neuroleptics and learning: Effects of haloperidol, molindone, mesoridazine and thioridazine on the behavior of pigeons under a repeated acquisition procedureJ. Pharmacol. Exp. Ther.255(3),1240-1245(1990)
